Metaplastic carcinoma of breast: a report of two cases

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dc.contributor.authorYahaya, James
dc.contributor.authorMremi, Alex
dc.date.accessioned2021-05-24T06:39:44Z
dc.date.available2021-05-24T06:39:44Z
dc.date.issued2020
dc.descriptionAbstract. Full text article available at https://doi.org/10.1093/omcr/omaa070en_US
dc.description.abstractThe pathogenesis of metaplastic breast carcinoma (MBC) is still debatable and it has been hypothesized that MBC develops as a result of transformation of epithelial cells into mesenchymal cells along with formation of a favorable tumor microenvironment. This favorable tumor microenvironment helps the transformed cells to undergo further mutations and clonal expansion. Case 1 was a 42-year old female with a 1-year history of a right breast fungating mass which was histologically confirmed to be matrix-producing type of MBC. Case 2 was a 47-year old female who presented with a recurrent left breast mass. Histologically, the tumor was confirmed to be carcinosarcomatous type of MBC. MBC is a rare, heterogeneous tumor with poor prognosis due to its aggressive behavior. It is more likely to mimic other benign breast conditions, therefore contributing to delay of diagnosis as it was for both of our patients herein presented.en_US
dc.identifier.citationYahaya, J., & Mremi, A. (2020). Metaplastic carcinoma of breast: a report of two cases. Oxford Medical Case Reports, 2020(9).en_US
dc.identifier.otherDOI: https://doi.org/10.1093/omcr/omaa070
dc.identifier.urihttp://hdl.handle.net/20.500.12661/3176
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.subjectMetaplasticen_US
dc.subjectCarcinomaen_US
dc.subjectBreasten_US
dc.subjectChondroiden_US
dc.subjectPoor prognosisen_US
dc.subjectBreast tumoren_US
dc.subjectMetaplastic Breast Carcinomaen_US
dc.subjectMBCen_US
dc.subjectBreast chemotherapyen_US
dc.subjectTumor microenvironmenten_US
dc.titleMetaplastic carcinoma of breast: a report of two casesen_US
dc.typeArticleen_US
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