Amani, Z.2024-03-122024-03-122023Amani, Z. (2023). Cure model for end-stage chronic kidney disease patients at Benjamin Mkapa hospital, Dodoma -Tanzania, (Master's Dissertation) The University of Dodoma.https://repository.udom.ac.tz/handle/20.500.12661/4257Cure modelling is a contemporary approach to survival analysis used when some subjects in the study never experience the event of interest. Cure models have been an area of interest and active research in the last three decades. This study used cure modelling approach for survival analysis of end-stage chronic kidney disease (CKD) at Benjamin Mkapa Hospital (BMH), Dodoma-Tanzania. The purpose of this study was to fit cure model for end stage CKD patients, to evaluate cure probabilities for end stage CKD treatments and to assess the cure probabilities due to influence of treatments’ sponsorship factor for survival of end stage CKD patients. The retrospective study was conducted from December, 2021 to June, 2018 for a follow up time of approximately 172 weeks. The cure model was fitted by using the exponentiated half-logistic as a baseline distribution. The comparison of cure rate between haemodialysis and post kidney transplant treatments status as well as the cure rate due to influence of sponsorship status of end stage CKD patients was evaluated by cured probabilities from the fitted model. The findings indicate that general cure probability for end stage CKD patients was 37% whereas the cure probabilities for health insurance sponsored and self-sponsored patients were 46% and 5.3% respectively. Self-sponsored patients were at higher risk of death than insurance sponsored-patients. Similarly, post kidney patients had 94% cure probability while haemodialysis patients had 38% cure probability. This is a call to government institutions and various health stakeholders to improve CKD awareness campaign among Tanzanians and intervene CKD treatments in order to increase longevity especially for self-sponsored end stage CKD patients. Moreover, Artificial Intelligence (AI) research should be conducted to intervene this heath challenge by innovating portable artificial kidneys for patients with end stage kidney diseases to minimize treatment’s costs and prolong their life.enThesis