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Browsing Chapters in a book by Author "Malima, Nyemaga Masanje"
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Item Metal oxide nanoparticles: a welcome development for targeting bacteria(Elsevier, 2020) Fasiku, Victoria Oluwaseun; Owonubi, Shesan John; Malima, Nyemaga Masanje; Hassan, Daniel; Revaprasadu, NeerishResistance to numerous antibiotics by a broad strain of microorganisms has become a global health concern. Conventional antibiotic agents and techniques have become inadequate to completely combat infectious diseases associated with this pathogen; thus, there is an increased rate of infectious disease mortality. In recent years, various scientific researchers have embarked on studies to explore alternate ways by which antibiotic resistance can be curbed. Nanotechnology has proven to be very promising, and a typical example of a nanotechnology strategy that has shown potential application in targeting different strains of resistant and nonresistant microbial strains is the treatment with metal oxide nanoparticles (MONPs). This chapter, therefore, focuses on different types of MONPs with antibacterial activities that have been studied, their method of synthesis, mechanisms of action, as well as the various fields that they can be potentially relevant in targeting pathogenic organisms.Item Metal oxide–based nanocomposites as antimicrobial and biomedical agents(Elsevier, 2020) Owonubi, Shesan John; Malima, Nyemaga Masanje; Revaprasadu, NeerishAntibiotic and multidrug resistance are among the great challenges facing researchers in designing and developing effective antimicrobial and biomedical agents. Thus, various strategies are being explored for the design and development of novel and effective biomedical and antimicrobial agents, one of which involves the fabrication of metal oxide–based nanocomposites (MOBNCs). Inspired by remarkable advances in the synthesis and characterization techniques over the years, antimicrobial metal oxide nanocomposites have in recent times been explored as potential antibiotics to fight the rise of infectious diseases. In this chapter, we present a review of the synthesis and characterization techniques of MOBNCs. This is preceded by a brief account and classification of metal oxide nanocomposites. We also highlight key findings on the efficacy of various MOBNCs regarding their antimicrobial activities to the target organisms. Finally, we provide a brief account of the potential biomedical applications of MOBNCs.