UDOM IR :: Browsing by Author "Ntunaguzi, Daudi"

Browsing by Author "Ntunaguzi, Daudi"

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Clinical profile of paediatric head and neck cancers at a tertiary hospital in Tanzania
(RBC / Rwanda Health Communication Centre, 2020) Abraham, Zephania Saitabau; Massawe, Enica Richard; Kahinga, Aveline Aloyce; Mapondella, Kassim Babu; Massawe, Willybroad Augustine; Swai, Henry; Mithe, Siwillis; Yahaya, James Joseph; Ntunaguzi, Daudi
Background: Paediatric head and neck cancers represent an important group of childhood cancers that require maximum attention at large. They are often diagnosed at advanced clinical stages at Muhimbili National Hospital (MNH). Objective: To describe the clinical profile of paediatric head and neck cancers at a tertiary hospital in Tanzania Method: A hospital based descriptive cross-sectional study was conducted involving 180 paediatric patients. Data were analyzed using SPSS program version 21. Results: A total of 180 paediatric patients were recruited where 61.1% were males and 38.9% were females. Majority belonged to the age group 0-5 years (53.9%). A total of 10 primary anatomical sites were found with the neck (cervical lymph node) predominating (36.1%), followed by the orbit/eye (34.4%) and the least anatomical sites were oral cavity (1.1%) and parapharyngeal space (0.5%). Leukocoria (93.9%), red eye (93.9%) and orbital cellulitis (77.6%) predominated in retinoblastoma but in patients with lymphomas, predominant features were night sweats (100%), weight loss (100%) and fevers (95.8%). Conclusion: The clinical profile depicted in this study appears to correlate with advanced clinical stages.
Clinico-pathological profile of nasopharyngeal carcinoma at Muhimbili national hospital, Dares Salaam, Tanzania
(Scientific Research Publishing, 2019) Abraham, Zephania Saitabau; Massawe, Enica Richard; Ntunaguzi, Daudi; Kahinga, Aveline Aloyce; Yahaya, James Joseph; Mithe, Siwillis Elizabeth
Background: Nasopharyngeal carcinoma (NPC) is an uncommon malignant tumor which has been reported invariably and cases have been encountered in Tanzania. Though rare they are associated with potential morbidity and mortality. The aim of this study was to characterize the clinico-pathological profile of such neoplasm in our set up. Methods: A retrospective review of 25 cases from hospital archives for 3 consecutive years was done where all patients with a histopathologically confirmed diagnosis of NPC were recruited. Data was analyzed using SPSS version 21. Results: Of the 25 eligible cases, 15 (60%) were males and 10 (40%) were females. Age range was 15-70 years. The peak age was 30-50 years in males and 50-59 years in females. Highest incidence was in the 5th decade. The commonest presenting features were cervical lymphadenopathy (92%) epistaxis (80%), hearing loss (80%) and nasal obstruction (76%) while the least common feature was seizures (4%). Histologically, undifferentiated carcinoma (76%) was the commonest variant while the least common one was differentiated non keratinizing squamous cell carcinoma (8%). Identifiable risk factors were consumption of salted smoked fish (80%), tobacco use (60%), alcohol intake (52%) and occupational exposure to wood dust (32%). Majority of patients (80%) were diagnosed with advanced stage of the disease (Stage IV). Conclusions: Findings from this study correlate with what has been reported elsewhere. Clinicians should have a higher index of suspicion in diagnosing NPC to enable early referral and prompt treatment of such malignant neoplasm.
Effectiveness of adenotonsillectomy in resolution of enuresis in children with sleep-disordered breathing: A hospital based prospective cohort study in Dar es Salaam, Tanzania
(Scientific Research Publishing, 2020) Abraham, Zephania S; Kahinga, Aveline A; Mapondella, Kassim B; Massawe, Enica R; Ntunaguzi, Daudi; Lengine, ,Emmanuel Ole
Background: Adenotonsillar hypertrophy remains to be the commonest causes of sleep disordered breathing in paediatric patients and has been implicated as a cause of primary and secondary enuresis. The aim of this study was to determine the effectiveness of adenotonsillectomy in resolution of enuresis in children with sleep-disordered breathing. Methods: A hospital based prospective cohort study was conducted at Ekenywa Specialised Hospital in Dar es Salaam, from May 2018 to February 2019. Two hundred children aged 3 to 15 years with obstructive adenotonsillar hypertrophy who were admitted ready to undergo adenotonsillectomy were evaluated. Upon such evaluation, the primary outcome was the number of bedwetting incidents (nocturnal enuresis) post-operatively compared with pre-operative incidents. Patients were kept under follow-up for 3 months. Data were collected using structured questionnaires regarding number of bedwetting incidents, type of enuresis (primary or secondary) and family history of enuresis. Data was analyzed using SPSS version 21 and p-values <0.05 were considered to be statistically significant. Results: Of 200 children admitted for adenotonsillectomy, 80 (40%) had a positive history of preoperative enuresis, including 35 (43.8%) girls and 45 (56.2%) boys. All parents for the children consented to participate in the study. Three months after adenotonsillectomy, enuresis had resolved completely in 50 (62.5%) children and had shown relative improvement in 25 (31.3%) children. Enuresis had not improved in the remaining 5 (6.3%) children (p<0.05). Conclusions: Findings from this study indicates that adenotonsillectomy can improve nocturnal enuresis and day-time incontinence in the majority of children with adenotonsillar hypertrophy.
An endoscopic study on the prevalence of accessory maxillary sinus ostium in patients with chronic rhinosinusitis in Dar es Salaam, Tanzania
(Dove Medical Press, 2020) Abraham, Zephania Saitabau; Kahinga, Aveline Aloyce; Mapondella, Kassim Babu; Massawe, Enica Richard; Ntunaguzi, Daudi
We aimed to determine the prevalence of and characterize accessory maxillary sinus ostium (AMO) in patients with chronic rhinosinusitis at a private health facility which serves the largest number of patients seeking treatment under private practice in Tanzanias largest city. Chronic rhinosinusitis is a common condition in otorhinolaryngology practice. It has been postulated in the available literature that accessory maxillary ostium may play a role in the development of chronic maxillary sinusitis. AMO has been frequently identified during routine nasal endoscopy. Its found in the medial wall of the maxillary sinus and located in the lateral wall of the nose. There is no study to date that has been conducted in Tanzania to characterize AMO in patients with chronic rhinosinusitis when seen at the clinic despite the growing use of endoscopy on an outpatient basis. Fifty adult patients with symptoms of chronic rhinosinusitis attending the ENT clinic on an outpatient basis were selected and then computerized tomography scan of the nose and paranasal sinuses (CT scan PNS) was performed. Nasal endoscopy was done to all patients to determine the presence and location of AMO. Of all the 50 studied patients, CT scan PNS depicted positive signs of rhinosinusitis in 35 patients (70%). Upon nasal endoscopy of the 35 patients, AMO was found in 25 patients (71.4%). Of the 15 patients with no depicted CRS upon CT scan, AMO was found in 4 (26.7%) patients. Nasal endoscopy provides additional evidence of obstruction of natural sinus ostia thus leading to chronic maxillary rhinosinusitis apart from CT PNS. Such observation is of importance to clinicians who are to execute management of these patients.
Indications and postoperative outcomes of pediatric adenotonsillectomy at a private hospital in Dar es Salaam, Tanzania
(Dove Medical Press, 2020) Abraham, Zephania Saitabau; Kahinga, Aveline Aloyce; Mapondella, Kassim Babu; Massawe, Enica Richard; Ntunaguzi, Daudi
We aimed to describe indications and postoperative outcomes of adenotonsillectomy among pediatric patients at a private hospital that serves the largest number of patients with otorhinolaryngological complaints seeking treatment in private health facilities in Tanzania’s largest city. Adenotonsillectomy is one of the commonest surgical procedures in otorhinolaryngology, and indications reported, though scarce in the literature, are infections and sleep-disordered breathing (SDB). Some studies in the last few decades have documented SDB superseding infection. There have been no studies in Tanzania documenting indications and postoperative outcomes of adenotonsillectomy, despite this being a commonly performed surgical procedure. A hospital-based descriptive cross-sectional study was conducted from January to December 2018, where children aged 0– 18 years who had undergone adenotonsillectomy at a private hospital were recruited. Data were analyzed using SPSS version 21. A total of 350 patients aged 0– 18 years were recruited: 60% were children aged < 5 years, 35% 6– 11 years, and 5% 12– 17 years. SDB accounted for a total of 247 (70.5%) indications, while infection accounted for only 60 (17.1%), and when both indications were combined, it accounted for 43 (12.4%) cases. SDB as an indication was proportionally higher in younger children, while infection was higher in older children. Postoperative hemorrhage was encountered in five patients (1.4%). Secondary hemorrhage predominated in four cases (80%), whilst one patient (20%) had primary hemorrhage. Sepsis at the surgical site was found to be the cause for all four patients (100%) with secondary hemorrhage, and the patient with primary hemorrhage had isolated thrombocytopenia as the underlying cause of hemorrhage. SDB was the commonest indication for adenotonsillectomy and postoperative complications were rare encounter, with secondary hemorrhage being predominant.
Lupus vulgaris of the external nose in a paediatric patient: a case report from Muhimbili national hospital, Tanzania
(University of Rwanda, 2019) Saitabau, Abraham Zephania; Ndeserua, Moshi; Enica, Richard; Ntunaguzi, Daudi
Lupus vulgaris is the most common form of cutaneous tuberculosis which usually occurs in patients who have been previously sensitized to Mycobacterium tuberculosis. We present a case of a 4-year-old girl who was diagnosed to have lupus vulgaris clinically and was then confirmed histopathologically. On local examination, the patient had irregularly bordered, well demarcated, whitish to reddish lesion on her external nose. The histopathological examination showed many dermal stromal granulomas of epithelioid cells, many multinucleated giant cells of Langhans type. This case report is therefore to emphasize on the importance of early diagnosis of lupus vulgaris of the external nose both clinically and on histopathological basis so as to avoid its destructive consequences which are mainly erosion of the external nose, nasal cavity and the face and in rare occasions, possible development of a carcinoma of squamous cell type.
Pattern and causes of tympanic membrane perforation at a private hospital in Dar es Salaam, Tanzania
(South Sudan Doctors' Association, 2019) Abraham, Zephania Saitabau; Kahinga, Aveline Aloyce; Mapondella, Kassim Babu; Massawe, Enica Richard; Lengine, Emmanuel Ole; Ntunaguzi, Daudi
Introduction: There is variation in the size, shape and position of tympanic membrane perforations; the degree of conductive hearing loss depends on the size and position of perforation. Objective: To determine the pattern and causes of tympanic membrane perforation at a private health facility in Tanzania Method: A hospital-based cross-sectional study in the ENT clinic at Ekenywa Specialised Hospital was conducted from January to May 2019. Ears were examined thoroughly by an Otorhinolaryngologist. Data were analysed using SPSS Version 21 Results: Two hundred and fifty patients were examined and 50 (20%) were found to have tympanic membrane perforations. Thirty (60%) were new patients while twenty (40%) were under review. Most 35(70%) were males. Central perforation predominated in 30 (60%), followed by subtotal in 10 (20%), total in 8 (16%) and marginal perforations in 2 (4%). The left ear was more affected in (60%) than the right ear. Bilateral perforations accounted for 5 (10%) of cases. Chronic suppurative otitis media was found in 35 (70%); other causes were acute suppurative otitis media in 13 (26%) and trauma in 2 (4%) patients Conclusions: The clinical picture depicted in this study is similar to that found elsewhere. There is a need for prompt diagnosis of tympanic membrane perforation. Proper education on ear care in patients with perforated tympanic membrane is of paramount importance.
Prevalence and etiological agents for chronic suppurative otitis media in a tertiary hospital in Tanzania
(Springer, 2019) Abraham, Zephania Saitabau; Ntunaguzi, Daudi; Kahinga, Aveline Aloyce; Mapondella, Kassim Babu; Massawe, Enica Richard; Nkuwi, Emmanuel James; Nkya, Aslam
Objective: Chronic suppurative otitis media is among the most common otological condition reported in otorhinolaryngology practice commonly attributing to preventable hearing loss. The aim of this study was to determine the prevalence and etiological agents for chronic suppurative otitis media in our department. Results: A total of 5591 patients were recruited in this study and only 79 (1.4%) had chronic suppurative otitis media. A male preponderance 43 (54.4%) was noted in this study and the left ear (58.2%) was more commonly affected compared to the right ear. Central perforation was the commonest pattern of presentation and was reported in 53% of cases though none had attic perforation. Of the 81 processed ear swabs, microbial growth was seen in majority 80 (98.8%) whilst one sample showed no microbial growth whereas 52.5% had polymicrobial growth. Among the isolates, most were gram negative species accounting for 59.7% while gram positive bacteria accounted for 25.6% and fungi accounted for 14.7%. Most of these isolates were facultative anaerobes. Klebsiella pneumoniae (20.2%) was the commonest isolates while Escherichia coli and Pseudomonas aeruginosa were equally least isolated (10.9%). Tested isolates were most sensitive to Ciprofloxacin, Gentamycin, Ceftriaxone and Amikacin and least sensitive to Amoxicillin/ clavulanic acid and Ampicillin.
Prevalence of chronic rhinosinusitis at Muhimbili national hospital, Dar es Salaam
(The South Sudan Doctors Association, 2019) Abraham, Zephania Saitabau; Gabriel, Rafael; Kahinga, Aveline Aloyce; Ntunaguzi, Daudi; Mapondella, Kassim Babu; Massawe, Enica Richard
Introduction: Chronic rhinosinusitis (CRS) affects people of all ages worldwide and has significant socio-economic impact. Data on chronic rhinosinusitis are scarce. Objective: To determine the prevalence of CRS among patients attending the Otorhinolaryngology Department at Muhimbili National Hospital (MNH). Method: This was a hospital based descriptive cross-sectional study where 56 patients with CRS were recruited from July to December 2015 after meeting the criteria set by American Academy of Otorhinolaryngology Head and Neck Surgery (AAOHNS). Data were analysed using SPSS program version 21. Results: The prevalence of CRS among 5321 patients was 1.07%; 51.8% were female and the highest proportion was aged 11-20 years. Bilaterality of disease was found in 62%. The maxillary sinus (83.9%) was the most affected sinus whilst the sphenoid sinus was least affected. There was good correlation between computerized tomography (CT) and intraoperative findings, anatomical variations and pathological features. Conclusion: CRS appears to be less prevalent at MNH than elsewhere with a tendency to bilaterality and maxillary sinus predominance similar to other studies.
A rare case report of aural myiasis in a 24-day old neonate in Tanzania
(Scientific Research Publishing, 2019) Abraham, Zephania Saitabau; Ntunaguzi, Daudi; Kahinga, Aveline Aloyce; Lengine, Emmanuel Ole; Mhamilawa, Lwidiko Edward; Massawe, Enica Richard
Aural myiasis refers to the infestation of the ear by the larvae of certain dipterous flies. The disease-producing flies prefer a warm and humid environment and higher incidence occur in tropics and subtropics of Africa and America. Aural myiasis is rare during neonatal life and children with tendencies of poking the ear need immediate review by otorhinolaryngologists for thorough otological review. The objective is thus to report the case of a 24-day old neonate who was diagnosed to have aural myiasis upon otoendoscopy at a private health facility in Tanzania. This is the first reported case of neonatal aural myiasis in our country. Neonates with tendencies to poke ears and with irritability should be handled with care by having immediate Otorhinolaryngologist review to exclude aural pathologies such as aural myiasis. Removal of the maggot, instilling ototopical antibiotics admixed with aural antiseptics, systemic antibiotics and close follow up for meticulous aural toilet remains the main stay in management of aural myiasis.
A rare incidental encounter of a foreign body in the nasopharynx during adenotonsillectomy: A case report from Tanzania
(Zambia Medical Association, 2019) Abraham, Zephania Saitabau; Massawe, Enica Richard; Mapondella, Kassim Babu; Kahinga, A veline Aloyce; Mithe, Siwillis; Ntunaguzi, Daudi
Foreign bodies may become lodged in various parts of the upper aerodigestive tract and establishing the presence of such foreign bodies is expected from health care practitioners. Foreign bodies may be classically organic or inorganic and their insertion into various parts of the aerodigestive tract may be deliberate or accidental. Majority of inhaled foreign bodies are reported in children and may even go unnoticed. There are scarce reported studies of foreign bodies in the nasopharynx. We are reporting an unusual case in which a foreign body in a child's nasopharynx went unnoticed for 9 months and was found incidentally during adenotonsillectomy.
A rare incidental encounter of unilateral choanal atresia during adenotonsillectomy in a 5-year-old child: a case report from Tanzania
(Mansa STM Publishers, 2020) Abraham, Zephania Saitabau; Massawe, Enica Richard; Mapondella, Kassim Babu; Kahinga, Aveline Aloyce; Ntunaguzi, Daudi
Unilateral choanal atresia refers to a congenital anomaly whereby a child is born with unilateral imperforate posterior nare. In most cases, the diagnosis is established several years after birth. The establishment of the diagnosis requires a high index of suspicion by clinicians. We report an unusual case of a 5-year-old girl who was diagnosed intraoperatively to have unilateral choanal atresia (right) during elective adenotonsillectomy after the failure of introducing a nasal catheter into the oropharynx and on digital palpation of the choanae intraorally. Endoscopic perforation of the membranous atretic choanal plate was done in the same sitting with adenotonsillectomy. The objective of this case report was thus to report an unusual case which went undiagnosed for 5 years and was diagnosed intraoperatively during elective adenotonsillectomy and also to review the few available pieces of the literature. To the best of our knowledge, this is so far the second reported case worldwide of unilateral choanal atresia incidentally diagnosed during adenotonsillectomy.
Spontaneous expulsion of an intrabronchial sharp metallic foreign body and migration to the gastrointestinal tract at Muhimbili national hospital: case report and literature review
(Elsevier LTD, 2020) Abrahama, Zephania Saitabau; Kahinga, Aveline Aloyce; Mapondella, Kassim Babu; Massawe, Enica Richard; Ntunaguzi, Daudi
Aspirated foreign bodies continue to pose challenges to Otorhinolaryngologists and are potentially life threatening thus an otorhinolaryngological emergency. The main stay of treatment of foreign bodies (FBs) in the tracheobronchial tree remains to be bronchoscopy while bearing in mind earlier and safer removal of such foreign bodies. Spontaneous expulsion of an Intrabronchial foreign body is a rare entity with few cases reported in the available literatures. We are reporting a rare case of a 3-year old male child who presented to otorhinolaryngology department with a 2-days history of foreign body inhalation (sharp metallic pin) prior admission which undergone spontaneous migration and went to be excreted in feaces after passing through the gastrointestinal tract. It is unwise, dangerous and inadvisable to wait for spontaneous expulsion in cases of intrabronchial foreign body but while preparing for endoscopy, a constant watch should be kept over the patient and every forceful bout of cough should be looked with suspicion of spontaneous expulsion and a danger of foreign body lodgment into subglottis during such rare but possible occurrence should be kept in mind. Its always worth to rule out the possibility of foreign body inhalation in children with sudden onset of difficulty in breathing to avoid diagnostic delays.

Browsing by Author "Ntunaguzi, Daudi"

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