Browsing by Author "Ripanda, Asha"
Now showing 1 - 12 of 12
Results Per Page
Sort Options
Item Biotransformation of 1,4-Dioxane by the Use of Bacteria in the Soil(Springer Nature Singapore, 2023) Miraji, Hossein; Ripanda, Asha; Bakari, Ramadhani; Sarma, HemenBackground: 1,4-Dioxane, also known as dioxane, is a water-miscible synthetic industrial chemical used as a stabilizer for chlorinated solvents and feedstock chemical for a wide range of industrial consumer products. It is a heterocyclic organic ether that, through consumer products and industrial, municipal, and domestic effluents, can get into the environment. Due to its volatility and miscibility, short-term exposure results in irritation of the nose, eyes, and throat, while excessive amounts damage the liver and kidney. Long-term exposure results in carcinogenicity to humans that may associate with death. Statement of problem: 1,4-Dioxane is nonbiodegradable in nature and hence persists in the environmental compartments; some methods such as UV peroxide oxidation, direct UV photolysis, and activated carbon adsorption were reported to be effective in the removal of dioxane in the environment. Yet, their adaptation challenges such as complex matrices, running costs, mass balance, and stoichiometry limitations hinder their efficiency. Finding: Mimicking natural or integrated techniques such as bacteriological transformation of dioxane via aerobic, anaerobic, microcosm, integrated microbial community, and co-metabolic techniques is among the robust eco-friendly technologies against these limitations. Soil matrix offers enormous microbial consortium for nature-based remediation of dioxane with high turnup than single microbial strains. Since bacteriological remediation offers adoptable, flexible, and quick implementation strategies that minimizes the use of synthetic chemicals, its fundamental understanding will be inevitable. Conclusion: Nature-based remediation of dioxane is an undoubtable future since apart from the natural occurrence of soil bacteria responsible for degradation, their natural adaptation flexibility, energy conservation, and release of harmless by-products without formation of secondary synergic harmful contaminants present a relatively affordable technique.Item Data from the batch adsorption of ciprofloxacin and lamivudine from synthetic solution using jamun seed ( Syzygium cumini ) biochar: Response surface methodology (RSM) optimization(Elsevier, 2023) Ripanda, Asha; Rwiza, Mwemezi J.; Nyanza, Elias Charles; Bakari, Ramadhani; Miraji, Hossein; Njau, Karoli N.; Vuai, Said Ali Hamad; Machunda, Revocatus L.This dataset expresses the experimental data on the batch adsorption of ciprofloxacin and lamivudine from synthetic solution using jamun seed (JS) (Syzygium cumini) biochar. Independent variables including concentration of pollutants (10-500 ppm), contact time (30–300 min), adsorbent dosage (1-1000 mg), pH (1-14) and adsorbent calcination temperature (250,300, 600 and 750 °C) were studied and optimized using Response Surface Methodology (RSM). Empirical models were developed to predict the maximum removal efficiency of ciprofloxacin and lamivudine, and the results were compared with the experimental data. The removal of polutants was more influenced by concentration, followed by adsorbent dosagage, pH, and contact time and the maximum removal reached 90%.Item Ecological consequences of microplastic pollution in sub-Saharan Africa aquatic ecosystems: An implication to environmental health(Elsevier BV, 2024) Moto, Edward; Hossein, Miraji; Bakari, Ramadhani; Mateso, Alfred Said; Selemani, Juma Rajabu; Nkrumah, Salma; Ripanda, Asha; Rwiza, Mwemezi J.; Nyanza, Elias Charles; Machunda, Revocatus L.Microplastic pollution (MPs) emerged as a significant environmental concern due to its persistent nature. These MPs particles endure in waters, soils, and even the atmosphere, posing potential threats to the entire ecosystem. Aquatic organisms are at risk of ingesting MPs, leading to accumulation in tissues, ultimately affecting entire food chain. This study aims to provide an overview of sources of MPs, distribution, and potential environmental impacts. MPs have been documented in various substances such as bottled water, salts, seafood, and even the air. However, the full extent of the health consequences on human exposure remains uncertain. Therefore, it is imperative that we draw public attention to the presence of these pollutants in the environment. To mitigate adverse effects of MPs, reducing plastic consumption, implementing improved waste management practices, and advocating sustainable behaviors are essential for well-being of natural ecosystems and the health human populations.Item Ecological consequences of microplastic pollution in sub-Saharan Africa aquatic ecosystems: An implication to environmental health(Elsevier BV, 2024) Moto, Edward; Hossein, Miraji; Bakari, Ramadhani; Mateso, Alfred Said; Selemani, Juma Rajabu; Nkrumah, Salma; Ripanda, Asha; Rwiza, Mwemezi J.; Nyanza, Elias Charles; Machunda, Revocatus L.Microplastic pollution (MPs) emerged as a significant environmental concern due to its persistent nature. These MPs particles endure in waters, soils, and even the atmosphere, posing potential threats to the entire ecosystem. Aquatic organisms are at risk of ingesting MPs, leading to accumulation in tissues, ultimately affecting entire food chain. This study aims to provide an overview of sources of MPs, distribution, and potential environmental impacts. MPs have been documented in various substances such as bottled water, salts, seafood, and even the air. However, the full extent of the health consequences on human exposure remains uncertain. Therefore, it is imperative that we draw public attention to the presence of these pollutants in the environment. To mitigate adverse effects of MPs, reducing plastic consumption, implementing improved waste management practices, and advocating sustainable behaviors are essential for well-being of natural ecosystems and the health human populations.Item Ethnomedicinal uses, phytochemistry and pharmacological study of Ocimum americanum L.: A review(Elsevier, 2023) Luanda, Amos; Ripanda, Asha; Sahini, Mtabazi G.; Makangara, John J.Background: Ocimum americanum L., commonly known as Hoary basil, is a wild aromatic shrub traditionally used to treat different ailments. Its leaves, flowers and aerial parts have been widely studied to evaluate its medicinal potential such as lowering blood pressure, treatment of microbial infections, malaria, cold, liver and eye problems. Purpose: This study aims to provide an in-depth review of ethnomedicinal uses, phytochemistry, and pharmacological activities of O. americanum, to evaluate its benefits, challenges and potential future prospects. Methods: All the information about O. americanum was collected from various platforms, including google scholar, PubMed, ScienceDirect, plants of the world online and Research4Life. The acceptance criteria of the collected information based on the PICOS model. The GRADE approach was used to analyze and evaluate the quality of the collected information. Results: This study showed that O. americanum has tremendous therapeutic potential to be integrated into mainstream medical practice to manage various medical conditions. The inconsistence of the phytoconstituents among the plant parts resulted in a significant variation of pharmacological activities. Plant originality, genetic variability and extraction techniques are among the factors contributing to the variation of phytoconstituents that are responsible for pharmacological activities. Conclusion: This study revealed that O. americanum is a potential medicinal plant for mitigating various medical conditions. However, future study should continue to focus on the bioactive compounds and their mechanisms of action. Additionally, the utilization of the O. americanum for the development of drugs as well as quality evaluation in clinical settings are highly recommended.Item Evaluation of potentiality of traditional hygienic practices for the mitigation of the 2019–2020 Corona Pandemic(Wiley, 2022) Ripanda, Asha; Miraji, Hossein; Sule, Khalfani; Nguruwe, Salvatory; Ngumba, Julias; Mtabazi, Geofrey Sahini; Vuai, Saidi HamadThe coronavirus outbreak threatens global well-being, costing thousands of lives and an unstable economy. Traditional hand-washing (HaWa) with clean water and hand-washing sanitizers (HaWaSas) are among WHO recommended practices against the outbreaks. HaWaSa and HaWa lacked proper quality monitoring evaluation that may pose health risks. The current study investigates the potential of traditional hygienic practices adopted to mitigate the 2019–2020 Pandemic. It involved assessing the effectiveness of 15 HaWaSa collected from the Dodoma market. Thirty volunteered participants were subjected to different hygienic practices involving HaWa and HaWaSa. The obtained hand-swabbed samples were subjected to the streak plate technique for inoculation, followed by counting colonies. The results revealed that, among the collected HaWaSa brands, only 33.3% were certified by the Tanzania Bureau of Standards (TBS). In the setting under no hand-wash, each client had a different number of colony counts. HaWa did not eliminate all colonies since water acted as a secondary source while only one sanitizer proved effective. The p-values obtained in either setting were greater than 0.05, indicating that each variable was independent. Despite global awareness and fighting against the Coronavirus Disease 2019 (Covid-19) outbreak, quality monitoring of all diagnostic tools, preventive HaWaSa, and related drugs should be prioritized for human safeguard.Item Optimizing ciprofloxacin removal from water using jamun seed (Syzygium cumini) biochar: A sustainable approach for ecological protection(Elsevier BV, 2024) Ripanda, Asha; Rwiza, Mwemezi J.; Nyanza, Elias Charles; Bih, Linda Numph; Hossein, Miraji; Bakari, Ramadhani; Sigh, Somit Kumar; Reddy, Giridhar; Ravikumar, C.R.; Murthy, H.C. Ananda; Njau, Karoli N.; Vuai, Said Ali Hamad; Machunda, Revocatus L.Scientific interest in antimicrobial pollutants, such as ciprofloxacin, has increased. Due to spread of antibiotic-resistant bacteria, resistance genes, and their dissemination to the environment. Therefore, their remediation is necessary to ensure ecological sustainability. The current study aimed to optimise the removal of ciprofloxacin from synthetic water using jamun seed (JS) (Syzygium cumini) biochar using a response surface methodology (RSM). Result indicates ciprofloxacin elimination efficiency ranged between 32.46 and 94.95%, indicating the material can be improved and used for remediation of organics. The residual standard error of 4.4% were found for the predicted model, implying that the model is credible and can be used to predict future experimental findings. The R-squarred value for the improved Langmuir model's R2 is 0.9681 which is inclose agreement with the Freundlich isotherm, R2 0.9757. Therefore, JS biochar could be utilized for the remediation of ciprofloxacin from contaminated water and wastewater for ecological safety and sustainability.Item Optimizing ciprofloxacin removal from water using jamun seed (Syzygium cumini) biochar: A sustainable approach for ecological protection(Elsevier BV, 2024) Ripanda, Asha; Rwiza, Mwemezi J.; Nyanza, Elias Charles; Bih, Linda Numph; Hossein, Miraji; Bakari, Ramadhani; Sigh, Somit Kumar; Reddy, Giridhar; Ravikumar, C.R.; Murthy, H.C. Ananda; Njau, Karoli N.; Vuai, Said Ali Hamad; Machunda, Revocatus L.Scientific interest in antimicrobial pollutants, such as ciprofloxacin, has increased. Due to spread of antibiotic-resistant bacteria, resistance genes, and their dissemination to the environment. Therefore, their remediation is necessary to ensure ecological sustainability. The current study aimed to optimise the removal of ciprofloxacin from synthetic water using jamun seed (JS) (Syzygium cumini) biochar using a response surface methodology (RSM). Result indicates ciprofloxacin elimination efficiency ranged between 32.46 and 94.95%, indicating the material can be improved and used for remediation of organics. The residual standard error of 4.4% were found for the predicted model, implying that the model is credible and can be used to predict future experimental findings. The R-squarred value for the improved Langmuir model's R2 is 0.9681 which is inclose agreement with the Freundlich isotherm, R2 0.9757. Therefore, JS biochar could be utilized for the remediation of ciprofloxacin from contaminated water and wastewater for ecological safety and sustainability.Item Recent trend on Tetradenia riparia (Hochst.) Codd (Lamiaceae) for management of medical conditions(Elsevier, 2023) Luanda, Amos; Ripanda, AshaTetradenia riparia (Hochst.) Codd (Lamiaceae) is a medicinal plant traditionally utilized to manage various transmitted and non-transmitted diseases such as HIV/AIDS, malaria, respiratory problems and diabetes. All parts of this plant have been utilized and demonstrated a positive promise for managing medical conditions. Several studies have been conducted to evaluate its pharmacological potentials, such as antibacterial, anthel-mintic, larvicidal, antifungal, antileishmanial, antioxidant and insecticidal activities. Purpose: This review aims to address the potential of T riparia for managing medical conditions, challenges and future research directions. In particular, the bioactive compounds responsible for pharmacological properties are discussed. The well-explained relevant studies and the most appropriate studies based on the selected topic were chosen. The obtained information was analyzed to determine the outcome by screening sources by title, abstract, and whole work. The selected studies were chosen in an agreement between the authors. The relevant information was sorted systematically into titles and subtitles and compressively discussed. The information presented in this review is obtained from various online platforms such as Google scholar, Springer, ScienceDirect, Web of Science and PubMed by searching using specific terms and phrases. The selected works based on the inclusion criteria as agreed by all authors. The phytochemical profile of T. riparia revealed the presence of several phytoconstituents, which support the pharmacological potentials of the plant. Findings revealed that both T. riparia essential oil and extracts have significant medicinal potentials remarkable for mitigating medical conditions, but the former outperforms the latter in terms of pharmacological potentials. Additionally, T. riparia has potential prospects in major medical conditions like tuberculosis, diabetes, malaria, snake bites, gonorrhea, dental abscesses, gastroenteritis, diar-rhoea, etc.This study revealed that Tetradenia riparia is a promising medicinal plant that can be employed as an alternative medicine against various medical conditions.Item Removal of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbent(Elsevier, 2023) Ripanda, Asha; Rwiza, Mwemezi J.; Nyanza, Elias Charles; Bakari, Ramadhani; Miraji, Hossein; Njau, Karoli N.; Vuai, Said Ali Hamad; Machunda, Revocatus L.Antiviral drugs such as lamivudine have been globally identified in the environment and marked as emerging pollutants of concern due to their bioactive extremity. Following therapeutic uses, approximately 70% of the oral dose of lamivudine is eliminated renally as the parent drug. Concerns has been raised for neighbouring aquatic bodies due to effluent produced from production plants containing high concentrations of antiviral drugs. Antiviral drugs, such as lamivudine, are extremely bioactive, prompting interest in their urgent removal from the environment. The purpose of the present study was to optimize the removal of lamivudine from the synthetic solution using jamun seed (JS) (Syzygium cumini) biochar. The influence of sorption parameters such as pH, lamivudine concentration, adsorbent dosage, contact time, and calcination temperatures on the removal of lamivudine was investigated and optimized using a response surface methodology (SRM) based on optimal design. The results indicated that, a quadratic model best fits data with a model regression coefficient R2, adjusted R2, and predicted R2 of 0.9934, 0.9761 and 0.8340, respectively. The JS biochar calcined at 750°C, at pH 8, initial lamivudine concentration of 10 ppm and contact time of 30 min indicated a maximum experimental removal efficiency of 84.9%. The residual standard error (RSE) value was 3.5% implying that the model was reliable. Isotherm data for the adsorption of lamivudine on JS biochar followed the Freundlich isotherm, with an R2 value of 0.9977 while R2 for the modified Langmuir model was 0.9852. These findings indicated that JS biochar is potentially useful for removal of lamivudine, and other organics from contaminated water and wastewater effluents. Therefore, this study presents an environmentally friendly remedy against lamivudine for a healthier ecologyItem Removal of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbent(Elsevier BV, 2023) Ripanda, Asha; Rwiza, Mwemezi J.; Nyanza, Elias Charles; Bakari, Ramadhani; Miraji, Hossein; Njau, Karoli N.; Vuai, Said Ali Hamad; Machunda, Revocatus L.Antiviral drugs such as lamivudine have been globally identified in the environment and marked as emerging pollutants of concern due to their bioactive extremity. Following therapeutic uses, approximately 70% of the oral dose of lamivudine is eliminated renally as the parent drug. Concerns has been raised for neighbouring aquatic bodies due to effluent produced from production plants containing high concentrations of antiviral drugs. Antiviral drugs, such as lamivudine, are extremely bioactive, prompting interest in their urgent removal from the environment. The purpose of the present study was to optimize the removal of lamivudine from the synthetic solution using jamun seed (JS) (Syzygium cumini) biochar. The influence of sorption parameters such as pH, lamivudine concentration, adsorbent dosage, contact time, and calcination temperatures on the removal of lamivudine was investigated and optimized using a response surface methodology (SRM) based on optimal design. The results indicated that, a quadratic model best fits data with a model regression coefficient R2, adjusted R2, and predicted R2 of 0.9934, 0.9761 and 0.8340, respectively. The JS biochar calcined at 750 °C, at pH 8, initial lamivudine concentration of 10 ppm and contact time of 30 min indicated a maximum experimental removal efficiency of 84.9%. The residual standard error (RSE) value was 3.5% implying that the model was reliable. Isotherm data for the adsorption of lamivudine on JS biochar followed the Freundlich isotherm, with an R2 value of 0.9977 while R2 for the modified Langmuir model was 0.9852. These findings indicated that JS biochar is potentially useful for removal of lamivudine, and other organics from contaminated water and wastewater effluents. Therefore, this study presents an environmentally friendly remedy against lamivudine for a healthier ecology.Item Therapeutic potential of Equisetum arvense L. for management of medical conditions(Elsevier, 2023) Luanda, Amos; Ripanda, Asha; Makangara, John J.Background: Equisetum arvense L. has a long history of use in traditional medicines for treating ailments like digestive, inflammatory, respiratory and urinary disorders. Researchers have been focused on developing drugs from natural sources particularly the medicinal plants for global mitigation of medical conditions while protecting the environment. The use of natural products is one of the strategies that the WHO recommended to manage global medical conditions. The interest to use natural remedies as alternative medicines for management of medical conditions is increasing considerably. Purpose: This review intended to discuss the therapeutic potential of E. arvense for the mitigation of various diseases by providing up-to-date information on its benefits, challenges and potential future opportunities. Methods: The information is collected and systematically analysed from various online databases including Google scholar, ScienceDirect, Springer, Web of Science, PubMed and Plant of the World Online. Results: This study demonstrated the enormous therapeutic potential of E. arvense for the management of various ailments. The significant changes in the phytoconstituents amongst the plant parts have been observed, which correspond to the variation in its pharmacological properties. Several pharmacological activities of E. arvense such as anticancer, anti-inflammatory, antibacterial, antifungal and antidiabetics support its traditional uses. Conclusion: E. arvense has a lot of therapeutic promises for treating a number of health disorders. The extension of its clinical study requires further identification of the bioactive compounds, their modes of action as well as toxicological study. The existing therapeutic potential of E. arvense, suggesting that it is a suitable medicinal plant for management of medical conditions.