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Item Metal oxide–based nanocomposites as antimicrobial and biomedical agents(Elsevier, 2020) Owonubi, Shesan John; Malima, Nyemaga Masanje; Revaprasadu, NeerishAntibiotic and multidrug resistance are among the great challenges facing researchers in designing and developing effective antimicrobial and biomedical agents. Thus, various strategies are being explored for the design and development of novel and effective biomedical and antimicrobial agents, one of which involves the fabrication of metal oxide–based nanocomposites (MOBNCs). Inspired by remarkable advances in the synthesis and characterization techniques over the years, antimicrobial metal oxide nanocomposites have in recent times been explored as potential antibiotics to fight the rise of infectious diseases. In this chapter, we present a review of the synthesis and characterization techniques of MOBNCs. This is preceded by a brief account and classification of metal oxide nanocomposites. We also highlight key findings on the efficacy of various MOBNCs regarding their antimicrobial activities to the target organisms. Finally, we provide a brief account of the potential biomedical applications of MOBNCs.