A comparative in-vitro study on antimicrobial efficacy of on-market alcohol-based hand washing sanitizers towards combating microbes and its application in combating Covid-19 global outbreak

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dc.contributor.authorVuai, Said Ali Hamad
dc.contributor.authorSahini, Mtabazi Geofrey
dc.contributor.authorSule, Khalfani Salim
dc.contributor.authorRipanda, Asha Shabani
dc.contributor.authorMwanga, Hossein Miraji
dc.date.accessioned2023-05-25T10:24:55Z
dc.date.available2023-05-25T10:24:55Z
dc.date.issued2022
dc.descriptionFull text article. Also available at https://doi.org/10.1016/j.heliyon.2022.e11689en_US
dc.description.abstractThe coronavirus disease 2019 (COVID-19) outbreak has created endless social, economic, and political fear in the global human population. Measures employed include frequent washing hands and using alcohol-based hand sanitisers and hand rubs as instant hand hygiene products. Due to the need to mitigate the pandermic, there is an increase in the local production of alcohol-based hand sanitisers, whose quality and efficacy against germs and the virus are questionable. Therefore, the current study investigated the in-vitro antimicrobial efficacy of on-market alcohol-based handwashing sanitizers used to mitigate the Covid-19 global outbreak toward combating enveloped bacteria such as E. Coli, P. aeroginosa, S. aureus, and a fungus C. albicans. The antimicrobial effectiveness of alcohol-based hand sanitizer was performed by the agar well diffusion method, and the analysis of variance (ANOVA) model was used for statistical analysis. Results indicate that alcohol hand-based sanitizers were more effective in inhibiting P. aeroginosa, with a mean zone of inhibition of 12.47 mm, followed by E. coli, a gramnegative bacterium with a mean zone of inhibition of 12.13 mm than both S. aureus and C. albicans as grampositive bacteria, and fungi respectively had the same inhibition average of 11.40 mm. The overall mean diameter of inhibition was statistically significantly different among the fifteen tested products. Only one brand of alcohol-based hand sanitizers was the most effective in inhibiting microbes. Less effective sanitizers may impair Covid 19 mitigation efforts and put the population at risk instead of protecting it. Indicating the need for all materials used to mitigate Covid 19 pandermic, including alcohol-based hand sanitizers, to be evaluated and monitored to ensure public health safety.en_US
dc.identifier.citationVuai, S. A. H., Sahini, M. G., Sule, K. S., Ripanda, A. S., & Mwanga, H. M. (2022). A comparative in-vitro study on antimicrobial efficacy of on-market alcohol-based hand washing sanitizers towards combating microbes and its application in combating Covid-19 global outbreak. Heliyon, 8(11), e11689.en_US
dc.identifier.otherDOI: https://doi.org/10.1016/j.heliyon.2022.e11689
dc.identifier.urihttp://hdl.handle.net/20.500.12661/3995
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectCoronavirus diseaseen_US
dc.subjectCOVID-19en_US
dc.subjectPublic health safetyen_US
dc.subjectMitigation strategiesen_US
dc.subjectHand washing sanitizersen_US
dc.subjectAntimicrobial efficacyen_US
dc.subjectHand washingen_US
dc.subjectHand hygiene productsen_US
dc.subjectHand hygieneen_US
dc.subjectAlcohol-based handwashing sanitizersen_US
dc.subjectPandermicen_US
dc.subjectAntimicrobial effectivenessen_US
dc.subjectCoronavirus disease 2019en_US
dc.titleA comparative in-vitro study on antimicrobial efficacy of on-market alcohol-based hand washing sanitizers towards combating microbes and its application in combating Covid-19 global outbreaken_US
dc.typeArticleen_US
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