Colorectal cancer epidemiology in Tanzania: patterns in relation to dietary and lifestyle factors

dc.contributor.authorKatalambula, L.
dc.contributor.authorPetrucka, P.
dc.contributor.authorBuza, J.
dc.contributor.authorNgoma, T.
dc.date.accessioned2023-05-25T07:55:28Z
dc.date.available2023-05-25T07:55:28Z
dc.date.issued2018
dc.descriptionAbstract. Full text article available at https://ascopubs.org/doi/abs/10.1200/jgo.18.74000en_US
dc.description.abstractChronic non-communicable diseases are increasingly captured as contributing to morbidity and mortality in low and middle income countries. This study aimed to investigate the epidemiology of colorectal cancer and the potential modifiable local risk factors in Tanzania. A cross sectional retrospective chart audit study was conducted to establish the pattern and distribution of colorectal cancer, The Food Frequency Questionnaire and the Step® survey tool were used to collect data. Descriptive statistics, χ2 tests, and regression analysis were used and augmented by data visualization to display risk variable differences. Tanzania's colorectal cancer incidence has increased six times in the last decade in which major towns and cities of Dar es Salaam (20.2 per 100,000), Pwani (7.2 per 100,000), Kilimanjaro (4.4 per 100,000), Arusha (4.2 per 100,000), and Morogoro (3.6 per 100,000) had the highest percentage. This study reported that, almost 45% of the participants were hypertensive. Two major dietary patterns, namely “healthy” and “western”, existed among the study sample. Obesity was found in 25% of participants, whereas overweight was present in 28%; of note, the prevalence was higher in females (26.9%) than in males (23.6%) respectively. The prevalence of alcohol consumption was 21.5%, with a significantly lower rate of smoking (12.2%) noted within the study subjects. Both alcohol consumption and tobacco smoking were more common in men than women (22.7 vs. 20.6% and 24.5 vs. 3.2%, respectively). The prevalence of vigorous, moderate, and low physical activity for both sexes was 18.6%, 54.1% and 42.3%, respectively. Evidence from this study demonstrate that, like other NCDs CRC is increasing in Tanzania. Colon cancer is increasing at higher rate than rectal cancer seeming to align with change in lifestyle. Major towns and cities had the highest share of CRC patients. Diet, obesity, tobacco smoking, alcohol consumption, and sedentary behavior have potential role to play in the rising trend of CRC and other NCDs. We recommend a large longitudinal study with robust methodology which can establish cause and effect relationships between specific lifestyle behaviors and the incidence of colorectal cancer.en_US
dc.identifier.citationKatalambula, L., Petrucka, P., Buza, J., & Ngoma, T. (2018). Colorectal cancer epidemiology in Tanzania: Patterns in relation to dietary and lifestyle factors. Journal of Global Oncology, 4(2).en_US
dc.identifier.otherURL: https://ascopubs.org/doi/abs/10.1200/jgo.18.74000
dc.identifier.urihttp://hdl.handle.net/20.500.12661/3971
dc.language.isoenen_US
dc.publisherAmerican Society of Clinical Oncologyen_US
dc.subjectTanzaniaen_US
dc.subjectColorectal canceren_US
dc.subjectRectal canceren_US
dc.subjectColon canceren_US
dc.subjectColorectal cancer patientsen_US
dc.subjectChronic non-communicable diseasesen_US
dc.subjectLifestyle factorsen_US
dc.subjectDietary factorsen_US
dc.subjectColorectal cancer epidemiologyen_US
dc.titleColorectal cancer epidemiology in Tanzania: patterns in relation to dietary and lifestyle factorsen_US
dc.typeArticleen_US
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