Morphological features of tyrosine hydroxylase immunoreactive cells in the mouse islets of langerhans

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dc.contributor.authorGesase, Ainory P.
dc.contributor.authorSatoh, Y-I
dc.date.accessioned2022-12-12T08:23:32Z
dc.date.available2022-12-12T08:23:32Z
dc.date.issued2009
dc.descriptionAbstract: Full text article available at https://www.ajol.info/index.php/tjs/article/view/73528en_US
dc.description.abstractThe current immunohistochemical study used the antibody against tyrosine hydroxylase (TH) to observe the immunoreactive elements in the mouse pancreas. The results indicated the presence of immunoreactive nerve fibers and endocrine cells. The immunopositive nerve fibers appeared as thick and thin bundles; thick bundles were seen to run along the blood vessels giving out fine fibers to the wall. Varicose nerve fibers were seen in the islets of Langerhans and also in close association with the exocrine endpieces. The TH immunoreactive cells were oval-round in shape and some showed the central non-staining area and the dense staining peripheral zone. More than 80% of the islets of Langerhans contained the immunoreactive cells. Individual islet showed between 3-10 immunopositive cells and a few contained 1-2 cells. The TH immunopositive cells were widely distributed in the islets; they were seen in the centre, at the intermediate position and at the periphery of the islets. The exact role of the TH immunoreactive cells in the islets of Langerhans is not known. It is possible that they secrete tyrosine hydroxylase that may have some paracrine influence to the endocrine cells. Wide distribution of these cells in the islets indicates that they may regulate the entire population of the islets cellsen_US
dc.identifier.citationGesase, A. P., & Satoh, Y. I. (2009). Morphological Features of Tyrosine Hydroxylase Immunoreactive Cells in the Mouse Islets of Langerhans. Tanzania Journal of Science, 35.en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12661/3577
dc.language.isoenen_US
dc.publisherAJOLen_US
dc.subjectBalb/c mouseen_US
dc.subjectPancreasen_US
dc.subjectTyrosine hydroxylaseen_US
dc.subjectImmunohistochemistryen_US
dc.subjectTyrosine hydroxylaseen_US
dc.subjectTHen_US
dc.subjectImmunoreactive cellsen_US
dc.subjectImmunopositive nerve fibersen_US
dc.subjectLangerhans isletsen_US
dc.titleMorphological features of tyrosine hydroxylase immunoreactive cells in the mouse islets of langerhansen_US
dc.typeArticleen_US
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