Aquasomes: a novel nanocarrier system for drug delivery

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dc.contributor.authorAyom, Gwaza Eric
dc.contributor.authorMalima, Nyemaga Masanje
dc.contributor.authorOwonubi, Shesan John
dc.contributor.authorRevaprasadu, Neerish
dc.date.accessioned2023-05-22T13:19:13Z
dc.date.available2023-05-22T13:19:13Z
dc.date.issued2023
dc.descriptionAbstract. Full text book chapter available at https://doi.org/10.1016/B978-0-323-85785-7.00018-8en_US
dc.description.abstractAquasomes are three layered self-assembled nanoparticles that are emerging as drug carriers or systems for the delivery of drugs. They are composed of an inner core which is usually coated with a polyhydroxyl carbohydrate and a loaded drug. The solid nanocrystalline inner core provides the structural stability of the aquasomes while the carbohydrate coat shields the loaded drug against dehydration. These self-assembled particles maintain the conformational integrity of the loaded drugs and hence have been exploited as carriers of drugs including insulin, hemoglobin, oxygen, antigens, and antibodies. This system of drug delivery has also been shown to improve the solubility of poorly soluble drugs. This chapter presents aquasomes’ preparation, properties, applications, and potential as drug carriers.en_US
dc.identifier.citationAyom, G. E., Malima, N. M., Owonubi, S. J., & Revaprasadu, N. (2023). Aquasomes: a novel nanocarrier system for drug delivery. In Advanced Nanoformulations, Theranostic Nanosystems, 3: 281-301. Academic Press.en_US
dc.identifier.otherDOI: https://doi.org/10.1016/B978-0-323-85785-7.00018-8
dc.identifier.urihttp://hdl.handle.net/20.500.12661/3786
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectBioactive agenten_US
dc.subjectOuter layeren_US
dc.subjectInner core materialen_US
dc.subjectDrug vehiclesen_US
dc.subjectAquasomesen_US
dc.subjectDrug deliveryen_US
dc.subjectNanocarrier systemen_US
dc.subjectNanoparticlesen_US
dc.subjectDrug carriersen_US
dc.subjectDrug deliveryen_US
dc.titleAquasomes: a novel nanocarrier system for drug deliveryen_US
dc.typeBook chapteren_US
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