Clinical predictors of malaria, acute bacterial meningitis and treatment outcomes among febrile children admitted with altered mental status in Northwestern Tanzania

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dc.contributor.authorJumanne, Shakilu
dc.contributor.authorMeda, John
dc.contributor.authorHokororo, Adolfine
dc.contributor.authorLeshabari, Kelvin
dc.date.accessioned2020-03-24T11:34:23Z
dc.date.available2020-03-24T11:34:23Z
dc.date.issued2017
dc.descriptionFull Text Article. Also available at: https://academic.oup.com/tropej/article/64/5/426/4682722en_US
dc.description.abstractBackground: Malaria and acute bacterial meningitis (ABM) are the leading infectious causes of febrile encephalopathy in malaria endemic settings. The clinical distinction of the two conditions is complicated by overlap in clinical features. Objective: To determine the clinical predictors for malaria, ABM and treatment outcome in febrile children aged 2 months to 12 years with altered mentation at two tertiary hospitals in Northwestern Tanzania. Methods: Prospective study of 103 children to document demographic data and physical examination findings, such as level of consciousness and meningeal irritations. Laboratory results for cerebrospinal fluid, hemoglobin, malaria and HIV were also evaluated. Results: Age>60 months and hemoglobin 5 g/dl were independent predictors of malaria; (p¼0.013 and 0.004, respectively). HIV infection was the only predictor of meningitis, p¼0.037, and mortality was high if the diagnosis was unconfirmed. Conclusions: Children with febrile encephalitic are more likely to have malaria than ABM if they have severe anemia.en_US
dc.identifier.citationJumanne, S., Meda, J., Hokororo, A., & Leshabari, K. (2018). Clinical predictors of malaria, acute bacterial meningitis and treatment outcomes among febrile children admitted with altered mental status in northwestern Tanzania. Journal of Tropical Pediatrics, 64(5), 426-433en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12661/2338
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.subjectMalariaen_US
dc.subjectMeningitisen_US
dc.subjectFebrile encephalopathyen_US
dc.subjectComaen_US
dc.subjectAcute bacterial meningitisen_US
dc.subjectAnemiaen_US
dc.subjectHIVen_US
dc.subjectHuman Immunodeficiency Virusen_US
dc.subjectHIV infectionen_US
dc.titleClinical predictors of malaria, acute bacterial meningitis and treatment outcomes among febrile children admitted with altered mental status in Northwestern Tanzaniaen_US
dc.typeArticleen_US
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