Predictors of microvascular complications in patients with type 2 diabetes mellitus at regional referral hospitals in the central zone, Tanzania: a cross-sectional study

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dc.contributor.authorShillah, Wilfred B.
dc.contributor.authorYahaya James J.
dc.contributor.authorMorgan, Emmanuel D.
dc.contributor.authorBintabara, Deogratius
dc.date.accessioned2024-08-20T04:52:44Z
dc.date.available2024-08-20T04:52:44Z
dc.date.issued2024
dc.descriptionFull-text. Available at https://doi.org/10.1038/s41598-024-55556-x
dc.description.abstractMicrovascular complications encompass a group of diseases which result from long-standing chronic effect of diabetes mellitus (DM). We aimed to determine the prevalence of microvascular complications and associated risk factors among patients with type 2 diabetes mellitus (T2DM). A cross-sectional analytical hospital-based study was conducted at Singida and Dodoma regional referral hospitals in Tanzania from December 2021 to September 2022. A total of 422 patients with T2DM were included in the analysis by determining the prevalence of microvascular complications and their predictors using multivariable logistic regression analysis. A two-tailed p value less than 0.05 was considered statistically significant. The prevalence of microvascular complications was 57.6% (n = 243) and diabetic retinopathy was the most common microvascular complication which accounted for 21.1% (n = 89). Having irregular physical activity (AOR = 7.27, 95% CI = 2.98–17.71, p < 0.001), never having physical activity (AOR = 2.38, 95% CI = 1.4–4.01, p = 0.013), being hypertensive (AOR = 5.0, 95% CI = 2.14–11.68, p = 0.030), having T2DM for more than 5 years (AOR = 2.74, 95% CI = 1.42–5.26, p = 0.025), being obese (AOR = 2.63, 95% CI = 1.22–5.68, p = 0.010), and taking anti-diabetic drugs irregularly (AOR = 1.94, 95% CI = 0.15–0.77, p < 0.001) were the predictors of microvascular complications. This study has revealed a significant proportion of microvascular complications in a cohort of patients with T2DM. Lack of regular physical activity, being obese, taking anti-diabetic drugs irregularly, presence of hypertension, and long-standing duration of the disease, were significantly associated with microvascular complications.
dc.identifier.citationShillah, W. B., Yahaya, J. J., Morgan, E. D., & Bintabara, D. (2024). Predictors of microvascular complications in patients with type 2 diabetes mellitus at regional referral hospitals in the central zone, Tanzania: a cross-sectional study. Scientific Reports, 14(1), 5035.
dc.identifier.doi10.1038/s41598-024-55556-x
dc.identifier.otherDOI: 10.1038/s41598-024-55556-x
dc.identifier.urihttps://repository.udom.ac.tz/handle/20.500.12661/4891
dc.language.isoen
dc.publisherSpringer Science and Business Media LLC
dc.relation.ispartofScientific Reports
dc.subjectMicrovascular complications
dc.subjectType 2 diabetes mellitus (T2DM)
dc.subjectPrevalence
dc.subjectRisk factors
dc.subjectDiabetic retinopathy
dc.subjectPhysical activity
dc.subjectHypertension
dc.subjectObesity
dc.subjectAnti-diabetic drugs
dc.subjectCross-sectional study
dc.subjectTanzania
dc.subjectSingida
dc.subjectDodoma
dc.subjectLogistic regression analysis
dc.subjectDisease duration
dc.subjectHealth outcomes
dc.subjectDiabetes management.
dc.titlePredictors of microvascular complications in patients with type 2 diabetes mellitus at regional referral hospitals in the central zone, Tanzania: a cross-sectional study
dc.typeArticle
oaire.citation.issue1
oaire.citation.volume14
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