Chemical profiling of Cannabis sativa from eleven Tanzanian regions

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dc.contributor.authorMhando, H. B.
dc.contributor.authorSahini, M. G.
dc.contributor.authorMakangara, J. J.
dc.date.accessioned2023-05-26T13:50:24Z
dc.date.available2023-05-26T13:50:24Z
dc.date.issued2023
dc.descriptionFull text article. Also available at https://www.cell.com/heliyon/pdf/S2405-8440(23)03099-2.pdfen_US
dc.description.abstractThe aim of this research was to investigate the chemical profiles of Cannabis sativa from 11 Tanzanian regions using preliminary tests as well as instrumental analyses with GC-MS and LCMS. Generally, all the seized samples tested positive for the presence of (Δ9-THC. The preliminary test with Duquenois method followed by chloroform addition revealed the presence of Δ9-tetrahydrocannabinol (Δ9-THC) in all the samples. GC-MS analyses of the samples revealed the presence of nine cannabinoids including Δ9-THC, Δ8-THC, cannabidivarol, cannabidiol, Δ9-tetrahydro cannabivarin (Δ9-THCV), cannabichromene, cannabinol, caryophyllene, and cannabicouramaronone, whereas LC-MS chemical profiling revealed the presence 24 chemical substances, including 4 cannabinoids, 15 different types of drugs and 5 amino acids. The Pwani region had the highest percentage composition of Δ9-THC (13.45%), the main psychoactive ingredient of Cannabis sativa, followed by Arusha (10.92%) and Singida (10.08%). The sample from Kilimanjaro had the lowest percentage of Δ9-THC (6.72%). Apart from cannabinoids, the majority of other chemical substances were found in the Dar es Salaam region sample, which could be attributed to the fact that the city is the epicenter of business rather than the cultivation area, implying that the samples were obtained from different sources and blended as a single package.en_US
dc.identifier.citationMhando, H. B., Sahini, M. G., & Makangara, J. J. (2023). Chemical profiling of Cannabis sativa from eleven Tanzanian regions. Heliyon, 9(5), e15892en_US
dc.identifier.otherURL: https://www.cell.com/heliyon/pdf/S2405-8440(23)03099-2.pdf
dc.identifier.otherDOI: https://doi.org/10.1016/j.heliyon.2023.e15892
dc.identifier.urihttp://hdl.handle.net/20.500.12661/4072
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectTanzania regionsen_US
dc.subjectTanzaniaen_US
dc.subjectCannabis sativaen_US
dc.subjectCannabinoidsen_US
dc.subjectChemical profilesen_US
dc.subjectDelta-9-tetrahydrocannabinolen_US
dc.subjectTetrahydrocannabivarinen_US
dc.subjectCannabidiolen_US
dc.titleChemical profiling of Cannabis sativa from eleven Tanzanian regionsen_US
dc.typeArticleen_US
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