Morpho-physiological features associated with menopause: recent knowledge and areas for future work

dc.contributor.authorMwampagatwa, Ipyana H.
dc.contributor.authorMwashambwa, Masumbuko Y.
dc.contributor.authorGesase, Ainory P.
dc.date.accessioned2021-08-20T08:34:47Z
dc.date.available2021-08-20T08:34:47Z
dc.date.issued2013
dc.descriptionAbstract. Full text article available at http://dx.doi.org/10.4314/thrb.v15i2.4en_US
dc.description.abstractMenopause is the permanent cessation of menstruation resulting from loss of ovarian follicular activity which happens as a result of depletion of primary follicles which is basically an aging effect. Depletion of ovarian follicles is reflected as declined production of oestradiol which is currently known to be central to the morphologic and physiological changes that happen during the climacteric, menopause and post menopause periods. The cessation of oestradiol production is much more pronounced in tissues with oestrogen receptors such as bones, brain, blood vessels, central nervous system and the skin. But generally little is known on the subject and in particular the bioactive substances involved in the process such that there are some symptoms that menopause women experience which not only defy clinicians but also challenge the management of the condition. This article is presented to shade light to what is currently known, what is not known and stimulate future research which may reveal more understanding and advance our knowledge on management of women throughout the climacteric and menopausal periods.en_US
dc.identifier.citationMwampagatwa, I. H., Mwashambwa, M. Y., & Gesase, A. P. (2013). Morpho-physiological features associated with menopause: recent knowledge and areas for future work. Tanzania Journal of Health Research, 15(2).en_US
dc.identifier.otherDOI:10.4314/thrb.v15i2.4
dc.identifier.urihttp://hdl.handle.net/20.500.12661/3290
dc.language.isoenen_US
dc.publisherHealth Research User's Trust Funden_US
dc.subjectMenopauseen_US
dc.subjectMenstruationen_US
dc.subjectOvarian folliclesen_US
dc.subjectMast cellsen_US
dc.subjectOestriadiolen_US
dc.subjectInhibinen_US
dc.titleMorpho-physiological features associated with menopause: recent knowledge and areas for future worken_US
dc.typeArticleen_US
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