Analysis of phytoconstituents of medicinal plants for the treatment (management) of type 2 diabetes mellitus (T2DM): a review
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Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
AkiNik Publications
Abstract
Gradual development of hyperglycemia, hyperlipideamea, insulin resistance, beta cell dysfunction, defects in GLUT4 translocation and insulin signaling receptors etc. lead to the development of type 2 diabetes mellitus, T2DM. The parallel research focuses on glucose homeostasis is gluconeogenesis/glycogenesis, absorption of glucose by gut and re-absorption of glucose by kidney etc. Different medicinal plants have different phyto-molecules which can be used for the treatment of the above said defects/metabolic syndromes. The effect of some phyto-molecules used for the treatment of T2DM can be compared with the already existing drugs and the phyto-molecules may not have side effects. Extraction and use of suitable phyto-molecules in the form of crude drugs for the treatment of the above said defects/metabolic syndromes are now on the research focus and this review analyzes the various phyto-molecules involved in the treatment of these different defects/metabolic syndromes of T2DM. Formulation of crude drug containing effective phyto-molecules from poly-herbs to activate different pathways, to treat the metabolic syndromes and to increase the health of the islet cells is the need of the hour.
Description
Abstract. Full text article available at https://www.phytojournal.com/archives/2018/vol7issue2/PartAY/7-2-273-414.pdf
Keywords
Diabetes mellitus, Medicinal plants, Hyperglycemia, Nutrition, Diabetic complications, Phytoconstituents, Metabolic syndromes, Poly-herbal, Crude drug, Phyto-molecules
Citation
Raj, R., Awan, M. T., Kumari, K., & Navis, S. (2018). Analysis of phytoconstituents of medicinal plants for the treatment (management) of type 2 diabetes mellitus (T2DM): a review. Journal of Pharmacognosy and Phytochemistry, 7(2), 3657-3664