Prevalence and risk factors of mortality among adult HIV patients initiating ART in rural setting of HIV care and treatment services in North western Tanzania: a retrospective cohort study

dc.contributor.authorGunda, Daniel Wilfred
dc.contributor.authorNkandala, Igembe
dc.contributor.authorKilonzo, Semvua Bukheti
dc.contributor.authorKilangi, Boniface Bartholomew
dc.contributor.authorMpondo, Bonaventura Cornel
dc.date.accessioned2021-05-18T08:32:50Z
dc.date.available2021-05-18T08:32:50Z
dc.date.issued2017
dc.descriptionFull text Article. Also available at https://doi.org/10.1155/2017/7075601en_US
dc.description.abstractIntroduction. HIV still causes high mortality despite use of ART. This study was designed to determine the prevalence and risk factors of mortality among HIV patients receiving ART in north western rural Tanzania. A retrospective study of HIV patients on ART was done at Sengerema in Mwanza, Tanzania. The data on demography, date of HIV diagnosis, WHO stage, opportunistic infections, CD4, hemoglobin, ART regimen,and time and outcome on treatment as dead or alive were collected and analyzed using STATA version 11. In total, 740 patients were studied. The median age was 35 (27–42) years with female predominance of 465 (62.8%). Of the participants, 261 (35.3%) had WHO stages 3 and 4 diseases. Most participants, 258 (34.9%), had baseline CD4 counts <200 cells/𝜇l. Deaths occurred in 86 (11.6%) patients which were independently associated with male gender (16.0% versus 9.0%, 𝑝 = 0.015), being divorced (OR=2.7,𝑝 < 0.001), WHO stages 3 and 4 (OR=2.3,𝑝 = 0.05), CD4<200 cells/𝜇l (OR=3.4, 𝑝 < 0.001), and severe anemia (OR=6.6, 𝑝 < 0.001). The mortality is high among HIV patients receiving ART in north western rural Tanzania. Universal testing could increase early diagnosis and treatment. A close follow-up ofat-risk patients within the first year of ART could reduce the mortality of this sub group of patients.en_US
dc.identifier.citationGunda, D. W., Nkandala, I., Kilonzo, S. B., Kilangi, B. B., & Mpondo, B. C. (2017). Prevalence and risk factors of mortality among adult HIV patients initiating ART in rural setting of HIV care and treatment services in North western Tanzania: a retrospective cohort study. Journal of Sexually Transmitted Diseases, 2017.en_US
dc.identifier.otherDOI: https://doi.org/10.1155/2017/7075601
dc.identifier.urihttp://hdl.handle.net/20.500.12661/3084
dc.language.isoenen_US
dc.publisherHindawien_US
dc.subjectAdult HIV patientsen_US
dc.subjectHIVen_US
dc.subjectHIV careen_US
dc.subjectHIV treatment servicesen_US
dc.subjectAIDen_US
dc.subjectAcquired immunodeficiency syndromeen_US
dc.subjectHuman immunodeficiency virusen_US
dc.subjectCD4en_US
dc.subjectWhite blood cellen_US
dc.titlePrevalence and risk factors of mortality among adult HIV patients initiating ART in rural setting of HIV care and treatment services in North western Tanzania: a retrospective cohort studyen_US
dc.typeArticleen_US
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