Ethnomedicinal uses, phytochemistry and pharmacological study of Ocimum americanum L.: A review

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dc.contributor.authorLuanda, Amos
dc.contributor.authorRipanda, Asha
dc.contributor.authorSahini, Mtabazi G.
dc.contributor.authorMakangara, John J.
dc.date.accessioned2023-05-23T06:17:56Z
dc.date.available2023-05-23T06:17:56Z
dc.date.issued2023
dc.descriptionFull text article. Also available at https://doi.org/10.1016/j.phyplu.2023.100433en_US
dc.description.abstractBackground: Ocimum americanum L., commonly known as Hoary basil, is a wild aromatic shrub traditionally used to treat different ailments. Its leaves, flowers and aerial parts have been widely studied to evaluate its medicinal potential such as lowering blood pressure, treatment of microbial infections, malaria, cold, liver and eye problems. Purpose: This study aims to provide an in-depth review of ethnomedicinal uses, phytochemistry, and pharmacological activities of O. americanum, to evaluate its benefits, challenges and potential future prospects. Methods: All the information about O. americanum was collected from various platforms, including google scholar, PubMed, ScienceDirect, plants of the world online and Research4Life. The acceptance criteria of the collected information based on the PICOS model. The GRADE approach was used to analyze and evaluate the quality of the collected information. Results: This study showed that O. americanum has tremendous therapeutic potential to be integrated into mainstream medical practice to manage various medical conditions. The inconsistence of the phytoconstituents among the plant parts resulted in a significant variation of pharmacological activities. Plant originality, genetic variability and extraction techniques are among the factors contributing to the variation of phytoconstituents that are responsible for pharmacological activities. Conclusion: This study revealed that O. americanum is a potential medicinal plant for mitigating various medical conditions. However, future study should continue to focus on the bioactive compounds and their mechanisms of action. Additionally, the utilization of the O. americanum for the development of drugs as well as quality evaluation in clinical settings are highly recommended.en_US
dc.identifier.citationLuanda, A., Ripanda, A., Sahini, M. G., & Makangara, J. J. (2023). Ethnomedicinal uses, phytochemistry and pharmacological study of Ocimum americanum L.: A review. Phytomedicine Plus, 100433.en_US
dc.identifier.otherDOI: https://doi.org/10.1016/j.phyplu.2023.100433
dc.identifier.urihttp://hdl.handle.net/20.500.12661/3807
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectMedical conditionsen_US
dc.subjectPharmacological activitiesen_US
dc.subjectEssential oilsen_US
dc.subjectOcimum americanum Len_US
dc.subjectEthnomedicinal usesen_US
dc.subjectHoary basilen_US
dc.subjectMedicinal planten_US
dc.subjectBioactive compoundsen_US
dc.subjectPharmacological activitiesen_US
dc.titleEthnomedicinal uses, phytochemistry and pharmacological study of Ocimum americanum L.: A reviewen_US
dc.typeArticleen_US
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