Characteristics and outcomes of patients with eclampsia and severe pre-eclampsia in a rural hospital in Western Tanzania: a retrospective medical record study

dc.contributor.authorMooij, Rob
dc.contributor.authorLugumila, Joseph
dc.contributor.authorMwashambwa, Masumbuko Y.
dc.contributor.authorMwampagatwa, Ipyana H.
dc.contributor.authorDillen, Jeroen van
dc.contributor.authorStekelenburg, Jelle
dc.date.accessioned2021-05-26T08:50:49Z
dc.date.available2021-05-26T08:50:49Z
dc.date.issued2015
dc.descriptionFull text article. Also available at https://doi.org/10.1186/s12884-015-0649-2en_US
dc.description.abstractEclampsia and pre-eclampsia are well-recognized causes of maternal and neonatal mortality in low income countries, but are never studied in a district hospital. In order to get reliable data to facilitate the hospitals obstetric audit a retrospective medical record study was performed in Ndala Hospital, Tanzania. All patients diagnosed with severe pre-eclampsia or eclampsia between July 2011 and December 2012 were included. Medical records were searched immediately following discharge or death. General patient characteristics, medical history, obstetrical history, possible risk factors, information about the current pregnancy, antenatal clinic attendance and prescribed therapy before admission were recorded. Symptoms and complications were noted. Statistical analysis was done with Epi Info®. Of the 3398 women who gave birth in the hospital 26 cases of severe pre-eclampsia and 55 cases of eclampsia were diagnosed (0.8 and 1.6 %). Six women with eclampsia died (case fatality rate 11 %). Convulsions in patients with eclampsia were classified as antepartum (44 %), intrapartum (42 %) and postpartum (15 %). Magnesium was given in 100 % of patients with eclampsia and was effective in controlling convulsions. Intravenous antihypertensive treatment was only started in 5 % of patients. Induction of labour was done in 29 patients (78 % of women who were not yet in labour). Delivery was spontaneous in 67 %, assisted vaginal (ventouse) in 14 % and by Caesarean section in 19 % of women. Perinatal deaths occurred in 30 % of women with eclampsia and 27 % of women with severe pre-eclampsia and were associated with low birth weight and prolonged time between admission and birth. 2.4 % of women were diagnosed with severe pre-eclampsia or eclampsia. The case fatality rate and overall perinatal mortality were comparable to other reports. Better outcomes could be achieved by better treatment of hypertension and starting induction of labour as soon as possible.en_US
dc.identifier.citationMooij, R., Lugumila, J., Mwashambwa, M. Y., Mwampagatwa, I. H., van Dillen, J., & Stekelenburg, J. (2015). Characteristics and outcomes of patients with eclampsia and severe pre-eclampsia in a rural hospital in Western Tanzania: a retrospective medical record study. BMC Pregnancy and Childbirth, 15(1), 1-7.en_US
dc.identifier.otherDOI: https://doi.org/10.1186/s12884-015-0649-2
dc.identifier.urihttp://hdl.handle.net/20.500.12661/3230
dc.language.isoenen_US
dc.publisherBMCen_US
dc.subjectEclampsiaen_US
dc.subjectSevere pre-eclampsiaen_US
dc.subjectMaternal mortalityen_US
dc.subjectNeonatal mortalityen_US
dc.subjectAntenatal clinicen_US
dc.subjectAntepartumen_US
dc.subjectIntrapartumen_US
dc.subjectPostpartumen_US
dc.subjectAntihypertensiveen_US
dc.subjectPerinatal deathsen_US
dc.subjectPerinatal mortalityen_US
dc.subjectHypertensionen_US
dc.titleCharacteristics and outcomes of patients with eclampsia and severe pre-eclampsia in a rural hospital in Western Tanzania: a retrospective medical record studyen_US
dc.typeArticleen_US
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