Prevalence predictors and outcomes of ventricular dyssynchrony among heart failure patients attending Benjamin Mkapa Hospital in Dodoma, Tanzania

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dc.contributor.authorBilikundi, Patrick
dc.date.accessioned2024-03-27T12:06:29Z
dc.date.available2024-03-27T12:06:29Z
dc.date.issued2023
dc.descriptionDissertation (MSc. Medicine)
dc.description.abstractIntroduction: Ventricular dyssynchrony (VD) is prevalent in heart failure (HF) patients with high cost of care and potentially poor outcomes. Nevertheless, little is known about VD, especially in developing countries. The study aimed at assessing the prevalence, predictors of VD, and outcomes of heart failure patients with ventricular dyssynchrony attending the cardiology department at Benjamin Mkapa referral hospital in Dodoma central Tanzania Methods: A prospective observational study design was conducted on participants aged 18yrs and above with heart failure attending Cardiology Department at Benjamin Mkapa Hospital. Heart failure was diagnosed using Framingham's score and enrolled patients with heart failure and ventricular dyssynchrony were followed up for six months. Baseline socio-demographic and clinical characteristics were taken during enrollment. The outcomes of interest during six months were worsening heart failure, readmission, and death. Continuous data were summarized as Mean (SD) or Median (IQR), and categorical data were summarized using proportions and frequencies. Binary logistic regression was used to determine predictors of Ventricular dyssynchrony among patients with heart failure using SPSS version 26. Results. 150 heart failure patients were included in the study with a mean age of 61.97±10.77, of whom 58.7% were females. The prevalence of ventricular dyssynchrony was 55%. Ventricular Mechanical Dyssynchrony was found to be 77(51.33%), (of whom interventricular mechanical dyssynchrony was 40(51.95%), and intraventricular dyssynchrony 37(48.05%). Electrical dyssynchrony was found in 57(38%) HF patients. Both mechanical and electrical dyssynchrony was seen in 51(34%) participants with HF. The independent predictors of ventricular dyssynchrony were: Dilated Cardiomyopathy (AOR 6.968, CI: 1.108-43.84, p =0.0386), Ischemic Heart Disease (AOR 20.818, CI: 3.871-111.967, p = 0.0004), NYHA IV (AOR, 6.968 CI: 1.288-32.39, p = 0.0233), reduced ejection fraction were the predictors of the development of ventricular dyssynchrony
dc.identifier.citationBilikundi, P. (2023). Prevalence predictors and outcomes of ventricular dyssynchrony among heart failure patients attending Benjamin Mkapa Hospital in Dodoma, Tanzania (Master's dissertation). The University of Dodoma.
dc.identifier.urihttps://repository.udom.ac.tz/handle/20.500.12661/4416
dc.language.isoen
dc.publisherThe University of Dodoma
dc.subjectVentricular dyssynchrony
dc.subjectVD
dc.subjectheart failure
dc.subjectHF
dc.subjectheart failure patients
dc.subjectBenjamin Mkapa Hospital
dc.subjectDodoma
dc.subjectIschemic heart disease
dc.titlePrevalence predictors and outcomes of ventricular dyssynchrony among heart failure patients attending Benjamin Mkapa Hospital in Dodoma, Tanzania
dc.typeThesis
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