Removal of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbent

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dc.contributor.authorRipanda, Asha
dc.contributor.authorRwiza, Mwemezi J.
dc.contributor.authorNyanza, Elias Charles
dc.contributor.authorBakari, Ramadhani
dc.contributor.authorMiraji, Hossein
dc.contributor.authorNjau, Karoli N.
dc.contributor.authorVuai, Said Ali Hamad
dc.contributor.authorMachunda, Revocatus L.
dc.date.accessioned2023-05-25T11:58:09Z
dc.date.available2023-05-25T11:58:09Z
dc.date.issued2023
dc.descriptionFull text article. Also available at https://doi.org/10.1016/j.emcon.2023.100232en_US
dc.description.abstractAntiviral drugs such as lamivudine have been globally identified in the environment and marked as emerging pollutants of concern due to their bioactive extremity. Following therapeutic uses, approximately 70% of the oral dose of lamivudine is eliminated renally as the parent drug. Concerns has been raised for neighbouring aquatic bodies due to effluent produced from production plants containing high concentrations of antiviral drugs. Antiviral drugs, such as lamivudine, are extremely bioactive, prompting interest in their urgent removal from the environment. The purpose of the present study was to optimize the removal of lamivudine from the synthetic solution using jamun seed (JS) (Syzygium cumini) biochar. The influence of sorption parameters such as pH, lamivudine concentration, adsorbent dosage, contact time, and calcination temperatures on the removal of lamivudine was investigated and optimized using a response surface methodology (SRM) based on optimal design. The results indicated that, a quadratic model best fits data with a model regression coefficient R2, adjusted R2, and predicted R2 of 0.9934, 0.9761 and 0.8340, respectively. The JS biochar calcined at 750°C, at pH 8, initial lamivudine concentration of 10 ppm and contact time of 30 min indicated a maximum experimental removal efficiency of 84.9%. The residual standard error (RSE) value was 3.5% implying that the model was reliable. Isotherm data for the adsorption of lamivudine on JS biochar followed the Freundlich isotherm, with an R2 value of 0.9977 while R2 for the modified Langmuir model was 0.9852. These findings indicated that JS biochar is potentially useful for removal of lamivudine, and other organics from contaminated water and wastewater effluents. Therefore, this study presents an environmentally friendly remedy against lamivudine for a healthier ecologyen_US
dc.identifier.citationRipanda, A., Rwiza, M. J., Nyanza, E. C., Bakari, R., Miraji, H., Njau, K. N., ... & Machunda, R. L. (2023). Removal of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbent. Emerging Contaminants, 9(3)en_US
dc.identifier.otherDOI: https://doi.org/10.1016/j.emcon.2023.100232
dc.identifier.urihttp://hdl.handle.net/20.500.12661/4001
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectSyzygium cuminien_US
dc.subjectSynthetic solutionen_US
dc.subjectLamivudineen_US
dc.subjectBiosorbentsen_US
dc.subjectEnvironmental contaminationen_US
dc.subjectEcosystem healthen_US
dc.subjectJamun seeden_US
dc.subjectBiochar adsorbenten_US
dc.subjectAntiviral drugsen_US
dc.subjectEmerging pollutantsen_US
dc.subjectEcologyen_US
dc.titleRemoval of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbenten_US
dc.typeArticleen_US
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