Removal of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbent

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dc.contributor.authorRipanda, Asha
dc.contributor.authorRwiza, Mwemezi J.
dc.contributor.authorNyanza, Elias Charles
dc.contributor.authorBakari, Ramadhani
dc.contributor.authorMiraji, Hossein
dc.contributor.authorNjau, Karoli N.
dc.contributor.authorVuai, Said Ali Hamad
dc.contributor.authorMachunda, Revocatus L.
dc.date.accessioned2024-08-19T06:40:08Z
dc.date.available2024-08-19T06:40:08Z
dc.date.issued2023
dc.descriptionFull-text. Available at https://doi.org/10.1016/j.emcon.2023.100232
dc.description.abstractAntiviral drugs such as lamivudine have been globally identified in the environment and marked as emerging pollutants of concern due to their bioactive extremity. Following therapeutic uses, approximately 70% of the oral dose of lamivudine is eliminated renally as the parent drug. Concerns has been raised for neighbouring aquatic bodies due to effluent produced from production plants containing high concentrations of antiviral drugs. Antiviral drugs, such as lamivudine, are extremely bioactive, prompting interest in their urgent removal from the environment. The purpose of the present study was to optimize the removal of lamivudine from the synthetic solution using jamun seed (JS) (Syzygium cumini) biochar. The influence of sorption parameters such as pH, lamivudine concentration, adsorbent dosage, contact time, and calcination temperatures on the removal of lamivudine was investigated and optimized using a response surface methodology (SRM) based on optimal design. The results indicated that, a quadratic model best fits data with a model regression coefficient R2, adjusted R2, and predicted R2 of 0.9934, 0.9761 and 0.8340, respectively. The JS biochar calcined at 750 °C, at pH 8, initial lamivudine concentration of 10 ppm and contact time of 30 min indicated a maximum experimental removal efficiency of 84.9%. The residual standard error (RSE) value was 3.5% implying that the model was reliable. Isotherm data for the adsorption of lamivudine on JS biochar followed the Freundlich isotherm, with an R2 value of 0.9977 while R2 for the modified Langmuir model was 0.9852. These findings indicated that JS biochar is potentially useful for removal of lamivudine, and other organics from contaminated water and wastewater effluents. Therefore, this study presents an environmentally friendly remedy against lamivudine for a healthier ecology.
dc.identifier.citationRipanda, A., Rwiza, M. J., Nyanza, E. C., Bakari, R., Miraji, H., Njau, K. N., ... & Machunda, R. L. (2023). Removal of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbent. Emerging Contaminants, 9(3), 100232.
dc.identifier.doi10.1016/j.emcon.2023.100232
dc.identifier.otherDOI: 10.1016/j.emcon.2023.100232
dc.identifier.urihttps://repository.udom.ac.tz/handle/20.500.12661/4721
dc.language.isoen
dc.publisherElsevier BV
dc.relation.ispartofEmerging Contaminants
dc.subjectAntiviral drugs
dc.subjectLamivudine
dc.subjectEmerging pollutants
dc.subjectBioactive extremity
dc.subjectEnvironmental contamination
dc.subjectAquatic bodies
dc.subjectEffluent
dc.subjectJamun seed biochar
dc.subjectSyzygium cumini
dc.subjectAdsorption
dc.subjectResponse surface methodology
dc.subjectSorption parameters
dc.subjectpH
dc.subjectCalcination temperature
dc.subjectFreundlich isotherm
dc.subjectLangmuir model
dc.subjectContaminated water
dc.subjectWastewater effluents
dc.subjectEnvironmental remediation.
dc.titleRemoval of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbent
dc.typeArticle
oaire.citation.issue3
oaire.citation.volume9
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