Assessing factors for adherence to antiretroviral therapy among adolescents and young adults (aged 10-24) in Tanzania: retrospective cohort study (2016-2020)
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Date
2022
Authors
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Journal ISSN
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Publisher
The University of Dodoma
Abstract
Adherence to ART is vital for combating HIV pandemic and reducing incidence of the disease. Effective and sustainable adherence to ART is a viable mechanism for viral suppression and for subsequent benefits which include immune restoration, prolonged survival, reduced resistance, improved quality of life and prevention of further HIV infections. This study therefore, intends to examine factors for adherence to antiretroviral therapy among adolescent and young adults (aged 10-24) receiving care in Tanzania. The study employed retrospective cohort study design where as data for this study was extracted from the CTC2 database held by MOH under NACP. The total of 100624 clients involved in this study. The adherence level for adolescent and young adults was about 82%. The findings indicated significant association between demographic factors.Thus, female has better adherence to ART than male(aRR=1.42, P<0.001), Clients aged 15-19 and 20-24 are less adherent to ART than those aged 10-14 (aRR=0.92, p<0.001 and aRR=0.80, p=0.024 respectively). Clinical factors and frequency of service delivery also were significant associated with adherence to ART(P<0.05). In clinical actors, clients not initiated ART on Same day and those confirmed TB were less adherent to ART (aRR=0.78, p<0.001) and (aRR=0.35,p=0.001) respectively. The risk of adherence for clients initiated 3MMD (aRR=1.53, p<0.001) and those in 6MMD (aRR=1.42, p=0.001) were bether than their references category. The findings suggest lagging bellow 95% overall adherence to ART for adolescents and young adults and mostly influenced by demographic and clinical characteristics and frequency of service delivery. The findings evolved the need for in-depth understanding of adolescent and young adult’s challenges on adherence to ART. There is need to address adherence to ART in equitable manner among type of health care facilities and ownerships.
Description
Master`s dissertation (Public Health)
Keywords
Antiretroviral therapy, Adolescents, Young adults, Tanzania, ART, HIV, Retrospective cohort study
Citation
Daud, E. (2022). Assessing factors for adherence to antiretroviral therapy among adolescents and young adults (aged 10-24) in Tanzania: retrospective cohort study (2016-2020) (Master;s dissertation). The University of Dodoma, Dodoma.