Trends in hospitalisation for human immunodeficiency virus in a tertiary hospital in Dar es Salaam, Tanzania: a case study

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dc.contributor.authorShayo, Grace A
dc.contributor.authorNagu, Tumaini
dc.contributor.authorMsele, Lilian
dc.contributor.authorMunseri, Patricia
dc.contributor.authorMbekenga, Columba
dc.contributor.authorKibusi, Steven
dc.contributor.authorPallangyo, Kisali
dc.contributor.authorMugusi, Ferdinand
dc.date.accessioned2020-09-02T07:52:40Z
dc.date.available2020-09-02T07:52:40Z
dc.date.issued2020
dc.descriptionFull-text article. Also available at https://doi.org/10.24248/eahrj.v4i1.627en_US
dc.description.abstractBackground: Reports on a systematic evaluation of the impact of antiretroviral therapy(ART) on patients’ hospitalisation in Sub Saharan Africa (SSA) and Tanzania, in particular, are scarce. We aimed at documenting the trends of hospital admissions at Muhimbili National Hospital (MNH) following scale-up of free access to ART in Tanzania. Methods: Records for all admissions at MNH from June 2005 to June 2015 were reviewed. We extracted data from the Hospital Information Management System as well as from patients’ charts. Data extracted included diagnosis at discharge, the reason for admission and thereafter assessed admission trends over the decade. We summarised the data as frequency and percentages. We compared proportions using the Chi-squared test, P<0.05 was deemed significant. Results: Overall there were 209,101 admissions during the study period (June 2005 to June 2015) and 7864/209,101 (3.8%) were due to HIV infection. Whereas 598/4,519 (13.2%) of all admissions in 2005 were due to HIV, only 345/13,119 (2.6%) of admissions in 2015 were HIV-related; showing a significant drop over time (P-value for trend < .001). Generally, females 3887/6679 (58.2%) were more likely to be admitted than males (41.8%). Median CD4 count for admitted HIV patients was 143 cells/μl. Majority of admissions occurred in the medical wards 3643/5310 (68.6%). Discharge diagnoses were Tuberculosis 1396/6482 (21.5%), anaemias 1016/6482 (15.6 %), malignancies 789/6482(12.2%), CNS infections 541/6482 (8.3%) and chronic kidney disease 308/6482 (4.8%). Three leading AIDS defining malignancies among hospitalised patients included Kaposi’s sarcoma 380/789 (48.2%), carcinoma of the cervix 77/789 (9.8%), and Non-Hodgkin’s lymphoma 44/789 (5.6%). Conclusion: Despite a drastic drop of HIV related admissions at Muhimbili National Hospital over the years, the infection remains a problem of the adults, largely females suffering from medical conditions and presenting with severe immunosuppression. Tuberculosis remained the most common opportunistic infection among hospitalized HIV infected patients. Anaemia and cancers became more important causes of admission than was diarrhoea which had been the most common among HIV infected patients in pre- ART.en_US
dc.identifier.citationShayo, G. A., Nagu, T., Msele, L., Munseri, P., Mbekenga, C., Kibusi, S., ... & Mugusi, F. (2020). Trends in hospitalization for human immunodeficiency virus in a tertiary hospital in Dar es Salaam, Tanzania: a case study. EA Health Research Journal, 4(1), 101-107.en_US
dc.identifier.otherDOI: 10.24248/eahrj.v4i1.627
dc.identifier.urihttp://hdl.handle.net/20.500.12661/2464
dc.language.isoenen_US
dc.publisherEast African Health Research Commissionen_US
dc.subjectHuman immunodeficiency virusen_US
dc.subjectHIVen_US
dc.subjectTertiary hospitalen_US
dc.subjectAntiretroviral therapyen_US
dc.subjectHospitalisationen_US
dc.subjectAcquired immunodeficiency syndromeen_US
dc.subjectAIDSen_US
dc.subjectDar es Salaamen_US
dc.subjectTanzaniaen_US
dc.titleTrends in hospitalisation for human immunodeficiency virus in a tertiary hospital in Dar es Salaam, Tanzania: a case studyen_US
dc.title.alternativeEast African Health Research Journalen_US
dc.typeArticleen_US
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