Prevalence, predictors and obstetrics outcomes of preterm premature rupture of membranes among pregnant women admitted at IRRH
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Date
2023
Authors
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Publisher
The University of Dodoma
Abstract
Background: Preterm premature rupture of membranes (PPROM) is one of the main
recognized causes of preterm deliveries and a significant contributor to maternal and
fetal morbidity and mortality. As such, details describing those affected and their
outcomes may prove important in mitigating its occurrence and effects. The burden of
and hierarchical information on the predictors of PPROM in this setting is inadequately
established.
Objective: This study's objective was to determine the prevalence, predictors and
obstetric outcomes following PPROM at Iringa regional referral hospital (IRRH).
Methodology: Hospital based cross-sectional study was carried out from September
2022 to January 2023. Participants in this study were 384 pregnant women who were
admitted in the IRRH antenatal ward. The diagnosis of PPROM was confirmed by
sterile speculum examination, and data were collected using questionnaires that the
researcher provided. Logistic regression analysis was done after descriptive statistics,
with the level of significance set at 0.05
Results: Among the 384 participants, 32 had PPROM giving a prevalence of 8%.
There were 98 babies delivered premature, of which PPROM accounted for 32.6%.
The independently significant predictors with statistically increased risks of PPROM
was attending antenatal clinic (ANC) less than 4 times (AOR = 4.14, 95% CI: 1.57 –
10.91, p = 0.004), having urinary tract infection when pregnant (AOR = 19.10, 95%
CI: 6.42 – 56.24, p = <0.001), genital tract infections when pregnant (AOR = 8.12,
95% CI: 1.77 – 37.20, p = 0.007), vaginal bleeding when pregnant (AOR = 9.79, 95%
CI: 1.93 – 49.61, p = 0.006) and having a history of previous PPROM (AOR = 6.61,
95% CI: 1.99 – 21.91, p = 0.002). According to the study, 87.5% (n = 28) of the babies
born to women who experienced PPROM had adverse outcomes, as did 44% (n = 14)
of the women who experienced PPROM.
Conclusion: The prevalence found is high compared to global. Predictors found were
such as genitourinary infections and vaginal bleeding during pregnancy, attending
ANC less than 4 times and previous history of PPROM. PPROM was also found to be
more associated with adverse outcomes. We recommend improvements on ANC
service use, screening, early diagnosis, and treatment of these predictors during
pregnancy
Description
Dissertation (MSc Medicine)
Keywords
obstetrics, pregnant women, preterm premature, preterm premature rupture, Iringa Referral Hospiatal
Citation
Titus, P. V. (2023). Prevalence, predictors and obstetrics outcomes of preterm premature rupture of membranes among pregnant women admitted at IRRH, (Master's dissertation). The University of Dodoma.